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KMID : 0604520170430020093
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Journal of the Society of Cosmetic Scientists of Korea
2017 Volume.43 No. 2 p.93 ~ p.102
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Anti-aging Cosmetic Application of Novel Multi-herbal Extract Composed of Nelumbo nucifera Leaves, Saururus chinensis and Orostachys japonica
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Baik Min-Young
Kim Jun-Hyeong
Lee Dae-Woo
Hwang Jae-Sung
Moon Eun-Jung
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Abstract
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In this study, various plant extracts were screened for the effective and safe skin care ingredient according to the antioxidant activity assay guidelines. We selected an optimized combination herbal extract, Charmzone extract (CZE), which composed of Nelumbo nucifera leaves, Saururus chinensis and Orostachys japonica. CZE exerted free radical scavenging activity. It reduced reactive oxygen species formation and increased total antioxidant capacities in human keratinocyte (HaCaT) and normal human dermal fibroblasts (NHDF). CZE also leaded procollagen type 1 secretion in NHDF and decreased cellular melanin contents in B16F10. The production of nitric oxide was decreased by CZE in lipopolysaccharide-stimulated RAW264.7 in a dose dependent manner. Therefore, it is concluded that CZE can be applied for naturally derived anti-aging functional skin care ingredient for anti-oxidation, wrinkle enhancement, whitening, anti-inflammation and wound healing of skin.
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KEYWORD
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Nelumbo nucifera leaf , Saururus chinensis , Orostachys japonica , anti-oxidant , anti-aging
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